Dr. Ilana Kepten
מחלקה:
Biotechnology Engineering
תפקיד נוכחי:
Senior Lecturer
Education :
Post graduate 2006, Bio-ethics program Portland State University
Ph.D.1991, Bilogy (molecular and cellular biology) The Technion – Israel Institute of Technology, Haifa, Israel
B.Sc.1985, Biology, Life sciences department Tel-Aviv university Israel
Research Interests
- 1. Applied Ethics in Biotechnology and emerging technologies
- 2. Rare mutions analysis in Cancer
Courses
- 1. Human Genetics
- 2. Cell Biology
- 3. Bioethics
Files
שם הקובץ
תאריך
סוג
Refereed Papers
- Kepten I. Induced Response in human cells to DNA Damage. Ph. D thesis , Israel Institute of Technology, Haifa, 1990.
- Ben- Ishai R, Scharf R, Sharon R, Kepten I. A Human cellular sequence implicated in trk oncogene activation is DNA damage inducible. PNAS 87: 6039: 1990.
- Kepten I, Rao KW, Kupfer S, Aylsworth AS. Hypogonadotropic hypogonadism in a dysmorphic patient with a minute proximal 8p deletion. Am J Hum Genet 4:318:1992.
- Dagan E, Kepten I, Ackermann T, Fried G,Bek D, Gershoni-Baruch R. Patterens of morbidity in highly selected patients with breast and /or ovarian cancer carriers of the three ancient mutations. AM J Hum Genet 61:337:1997
- Gershoni-Baruch R, Dagan E, Kepten I, Fried G. Co- segregation of BRCA1 185delAG mutation and 6174 del T in one single family. Eur J cancer, 33:2283 1997.
- Kepten I, Badarna K, Gershoni-Baruch R. Carrier frequency of the G47D mutation in the tyrosinase gene in individuals of Jewish Moroccan origin. Am J Hum Genet 61:1169:1997.
- Brik R, Shinawi M, Kepten I, Berent M, Gershoni-Barch R. Familial Mediterranean fever: Clinical and Genetic charactristics in a mixed pediatric population of Jewish and Arab patients. Pediatrics, 103:5, 1999.
- Kepten I, Shinawi M, Brik R, Gershoni-Barch R. Direct detection of common mutations in Familial Mediterranean fever using naturally occurring and primer mediated restriction fragment analysis. Human mutation, 14:91 1999. (In Brief #257)
- Oren I, Brook G, Gershoni-Baruch R , Kepten I, Tamir A, Shai L, Wolfovitz D. The D allele of the angiotensin converting enzyme gene contributes towards blood LDL – cholesterollevels and the presence of hypertension. Atherosclerosis 145: 267,1999.
- Gershoni-Baruch R, Dagan E, Fried G, Kepten I, Robinson E. BRCA1 and BRCA2 founder mutations in patients with bilateral breast cancer. Eur J Hum. Genet 7:833-836, 1999.
- Ustun C, Corless CL, Savage N, Fiskus W, Manaloor E, Heinrich MC, Lewis G, Ramalingam P, Kepten I, Jillella A, Bhalla K. Chemotherapy and dasatinib induce long-term hematologic and molecular remission in systemic mastocytosis with acute myeloid leukemia with KIT D816V. Leuk Res. 2009 May;33(5):735-41
- Heterogeneity of kinase inhibitor resistance mechanisms in GIST. Liegl B, Kepten I, Le C, Zhu M, Demetri GD, Heinrich MC, Fletcher CD, Corless CL, Fletcher JA. J Pathol. 2008 Sep;216(1):64-74.
Conference Proceedings and Abstracts
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Kepten I, Sharon R, Ben – Ishai R. Induced heat shock functions due to DNA damage in human Xp cells. DNA Repair workshop, Holland 1987.
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Mandel H, Berant M, Kepten I, Greenberg A, Levy N, Brenner B, Lanir N, Gershoni-Baruch R. Is heterozygosity for homocystinuria an independent risk factor for thrombosis? SSIEM 33rd Annual Symposium, Cardiff, 1996.
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Gershoni-Barch R, Dagan E, Kepten I, Fried G, Robinson E. Bilateral breast cancer and genetic suseceptibility.48th annual meeting of American Society of Human Genetics, Denver, colorado October 1998.
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Kepten I, Shinawi M, Brik R, Gershoni-Barch R. Familial Mediterranean fever: Jewish and Arab descent. 48th annual meeting of American Society of Human Genetics, Denver, Colorado October 1998.
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Robinson E, Gershoni-Baruch R, Dagan E, Kepten I, Fried G. BRCA1 and BRCA2 founder mutations in patients with bilateral breast cancer. Thirty-fifth annual meeting of American Society of Clinical Oncology, Atlanta, May 1999.
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Ilana Kepten, Bernadette Liegl, Claudia Le, Christopher D.M. Fletcher, Michael C. Heinrich, Jonathan A. Fletcher Christopher L. Corless. Molecular heterogeneity of imatinib resistance in GI stromal tumors (GISTs) AACR San- Diego 2008.
Academic Appointments
2009-present Senior Lecturer, ORT Braude College, Department of Biotechnology Engineering
2005-2008 Affiliated Research Assistant Professor in the VA Cancer Research Center – OHSU Portland, Oregon, US
2002-2005 Department-Head of the Biotechnology Engineering Department, ORT Braude Engineering College, Israel
1998-2002 Adjuct lecturer ORT Braude College, Department of Biotechnology Engineering
1991-1994 Post doctoral position, Division of Molecular Pathology .UNC Medical School, NC US
Teaching Experience
ORT Braude College of Engineering:
Graduate Courses:
Human genetics, Law and Ethics in clinical trials, The cellular and molecular basis of diseases.
Undergraduate Courses:
Cell Biology, Advanced technologies in molecular cell biology, Introduction to Bioethics,
Human genetics, Law and Ethics in clinical trials, The cellular and molecular basis of diseases.
Undergraduate Courses:
Cell Biology, Advanced technologies in molecular cell biology, Introduction to Bioethics,