Dr. Ilana Kepten

Dr. Ilana Kepten

Dr. Ilana Kepten

04-9901828
A3 room:1
מחלקה: Biotechnology Engineering
תפקיד נוכחי: Senior Lecturer

Education :

Post graduate 2006, Bio-ethics program Portland State University

Ph.D.1991, Bilogy (molecular and cellular biology) The Technion – Israel Institute of Technology, Haifa, Israel

B.Sc.1985, Biology, Life sciences department Tel-Aviv university Israel

Research Interests
  • 1. Applied Ethics in Biotechnology and emerging technologies
  • 2. Rare mutions analysis in Cancer
Courses
  • 1.  Human Genetics
  • 2. Cell Biology
  • 3. Bioethics

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Ilana_Kepten_CV
21/05/2019
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Refereed Papers

  1.  Kepten I. Induced Response in human cells to DNA Damage. Ph. D thesis , Israel Institute of Technology, Haifa, 1990.
  2.  Ben- Ishai R, Scharf R, Sharon R, Kepten I. A Human cellular sequence implicated in trk oncogene activation is DNA damage inducible. PNAS 87: 6039: 1990.
  3. Kepten I, Rao KW, Kupfer S, Aylsworth AS. Hypogonadotropic hypogonadism in a dysmorphic patient with a minute proximal 8p deletion. Am J Hum Genet 4:318:1992.
  4. Dagan E, Kepten I, Ackermann T, Fried G,Bek D, Gershoni-Baruch R. Patterens of morbidity in highly selected patients with breast and /or ovarian cancer carriers of the three ancient mutations. AM J Hum Genet 61:337:1997
  5. Gershoni-Baruch R, Dagan E, Kepten I, Fried G. Co- segregation of BRCA1 185delAG mutation and 6174 del T in one single family. Eur J cancer, 33:2283 1997.
  6.  Kepten I, Badarna K, Gershoni-Baruch R. Carrier frequency of the G47D mutation in the tyrosinase gene in individuals of Jewish Moroccan origin. Am J Hum Genet 61:1169:1997.
  7. Brik R, Shinawi M, Kepten I, Berent M, Gershoni-Barch R. Familial Mediterranean fever: Clinical and Genetic charactristics in a mixed pediatric population of Jewish and Arab patients. Pediatrics, 103:5, 1999.
  8. Kepten I, Shinawi M, Brik R, Gershoni-Barch R. Direct detection of common mutations in Familial Mediterranean fever using naturally occurring and primer mediated restriction fragment analysis. Human mutation, 14:91 1999. (In Brief #257)
  9. Oren I, Brook G, Gershoni-Baruch R , Kepten I, Tamir A, Shai L, Wolfovitz D. The D allele of the angiotensin converting enzyme gene contributes towards blood LDL – cholesterollevels and the presence of hypertension. Atherosclerosis 145: 267,1999.
  10. Gershoni-Baruch R, Dagan E, Fried G, Kepten I, Robinson E. BRCA1 and BRCA2 founder mutations in patients with bilateral breast cancer. Eur J Hum. Genet 7:833-836, 1999.
  11. Ustun C, Corless CL, Savage N, Fiskus W, Manaloor E, Heinrich MC, Lewis G, Ramalingam P, Kepten I, Jillella A, Bhalla K. Chemotherapy and dasatinib induce long-term hematologic and molecular remission in systemic mastocytosis with acute myeloid leukemia with KIT D816V. Leuk Res. 2009 May;33(5):735-41
  12. Heterogeneity of kinase inhibitor resistance mechanisms in GIST. Liegl B, Kepten I, Le C, Zhu M, Demetri GD, Heinrich MC, Fletcher CD, Corless CL, Fletcher JA. J Pathol. 2008 Sep;216(1):64-74.

Conference Proceedings and Abstracts

  1. Kepten I, Sharon R, Ben – Ishai R. Induced heat shock functions due to DNA damage in human Xp cells. DNA Repair workshop, Holland 1987.
  2. Mandel H, Berant M, Kepten I, Greenberg A, Levy N, Brenner B, Lanir N, Gershoni-Baruch R. Is heterozygosity for homocystinuria an independent risk factor for thrombosis? SSIEM 33rd Annual Symposium, Cardiff, 1996.
  3. Gershoni-Barch R, Dagan E, Kepten I, Fried G, Robinson E. Bilateral breast cancer and genetic suseceptibility.48th annual meeting of American Society of Human Genetics, Denver, colorado October 1998.
  4. Kepten I, Shinawi M, Brik R, Gershoni-Barch R. Familial Mediterranean fever: Jewish and Arab descent. 48th annual meeting of American Society of Human Genetics, Denver, Colorado October 1998.
  5. Robinson E, Gershoni-Baruch R, Dagan E, Kepten I, Fried G. BRCA1 and BRCA2 founder mutations in patients with bilateral breast cancer. Thirty-fifth annual meeting of American Society of Clinical Oncology, Atlanta, May 1999.
  6. Ilana Kepten, Bernadette Liegl, Claudia Le, Christopher D.M. Fletcher, Michael C. Heinrich, Jonathan A. Fletcher Christopher L. Corless. Molecular heterogeneity of imatinib resistance in GI stromal tumors (GISTs) AACR San- Diego 2008.

Academic Appointments

2009-present Senior Lecturer, ORT Braude College, Department of Biotechnology Engineering

2005-2008 Affiliated Research Assistant Professor in the VA Cancer Research Center –  OHSU Portland, Oregon, US

2002-2005 Department-Head of the Biotechnology Engineering Department, ORT Braude Engineering  College, Israel

1998-2002 Adjuct lecturer ORT Braude College, Department of Biotechnology Engineering

1991-1994 Post doctoral position, Division of Molecular Pathology .UNC Medical School, NC US

Teaching Experience

ORT Braude College of Engineering:
Graduate Courses:
Human genetics, Law and Ethics in clinical trials, The cellular and molecular basis of diseases.
Undergraduate Courses:
Cell Biology, Advanced technologies in molecular cell biology, Introduction to Bioethics,

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